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The WHO/HIVResNet Laboratory Operational Framework describes how WHO HIVResNet laboratories function to support national, regional, and global HIV drug resistance (HIVDR) surveillance by providing accurate genotyping results in a standardized format according to WHO specifications.
Keywords: HIV, laboratory services, drug resistance
With the 2016 Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection, WHO updated and launched new policy recommendations on the clinical and service delivery aspects of HIV treatment and care, and raised the bar to treat all PLHIV (Treat All). WHO has worked with countries to ensure uptake and implementation of these recommendations in support of the to the 90-90-90 targets.
This fact sheet present data for 194 WHO Member States – including 139 low- and middle-income countries – and 35 Fast-Track countries, respectively through November 2017.
The International Council of AIDS Service Organizations (ICASO) developed this brief to provide the HIV community with current information and analysis of new and updated clinical data on the effectiveness of antiretroviral therapy (ART) in preventing HIV transmission to sexual partners of people living with HIV. While the health benefits of treatment will always be the primary purpose of ART, it is vital that the secondary benefits to people living with HIV and their sexual partners be fully understood and communicated.
Keywords: HIV, ART, transmission, advocacy, prevention
The advent of point-of-care (POC) Early Infant Diagnosis (EID) technologies is a breakthrough that creates the opportunity to increase coverage of EID testing. It will allow same-day test results and enable the initiation of earlier treatment, as well as address some of the key limitations of conventional EID networks – in particular long turnaround times for tests and high rates of loss to follow up.
According to the WHO, about 2.3 million people are co-infected with HIV and the hepatitis C virus (HCV). Moreover, there were an estimated 1.75 million new hepatitis C virus (HCV) infections worldwide in 2015. HCV usually presents only mild symptoms, if any, until it is at an advanced stage, thereby making it difficult to recognize the disease early.
The World Health Organization was requested by Member States to develop a global priority pathogens list (global PPL) of antibiotic-resistant bacteria to help in prioritizing the research and development (R&D) of new and effective antibiotic treatments. To date, the selection of pathogens for R&D activities has been largely guided by small and large pharmaceutical companies according to a variety of parameters, such as perceived/unmet medical need, pressure of investors, market size, scientific discovery potential, and availability of specific technologies. Previous PPLs, issued by the Centers for Disease Control and Prevention.
The hepatitis C virus (HCV) has long since been a neglected disease, given long latency periods before any chronic illness manifests, and the low cure rate and numerous side effects of the pegylated interferon-ribavirin treatment (hereinafter PEGINF). However, of late, given the development of revolutionary drugs called direct-acting antivirals (DAAs) that can cure the disease in as little as 8 weeks, international interest, and with it, international financial investment, has peaked.
Infographic on hepatitis produced by WHO Regional Office for the Western Pacific.
This report presents background information on Kiribati, its health-care system and the national epidemiology of hepatitis. It then details review findings and recommendations under each priority area of action of the Regional Action Plan for Viral Hepatitis in the Western Pacific 2016–2020: broad-based advocacy and awareness, evidence-based policy guiding comprehensive hepatitis action, data supporting the hepatitis response, stopping transmission, and an accessible and effective treatment cascade.
Keywords: co-infection, transmission, treatment cascade, policy
Monitoring of individuals on ART is important to ensure treatment efficacy and improved health outcomes.
The 2016 WHO Consolidated Guidelines on the use of antiretroviral drugs for treating and preventing HIV infection include recommendations on routine monitoring and the diagnosis of treatment failure.
Keywords: HIV, ART, CD4, treatment, testing, monitoring