Hepatitis C Diagnostics Technology Landscape - 1st Edition. Murtagh MM. (2015)

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This report describes the current continuum of testing for HCV, which is complex and expensive, which means that it is very challenging to implement in resource-limited settings. It examines the platforms/tests that are currently available across the range of required HCV testing from screening to confirmation and genotyping, fibrosis staging and treatment monitoring. The report also considers how the testing cascade for HCV may be simplified with the availability of DAAs, which would help make HCV testing attainable in resource-limited settings. Finally, it looks at the pipeline of tests/platforms for HCV that could be delivered at or near the point of patient care.

 

Keywords: HIV, HCV, treatment, testing, monitoring

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Scaling up HIV Treatment for MSM in Bangkok: What Does It Take? — A Modelling and Costing Study. Zhang L, Phanuphak N, Henderson K, et al. (2015)

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The HIV epidemic amongst men who have sex with men (MSM) in Bangkok is substantial. The population size of MSM in Bangkok is 120,000-250,000, with approximately one-third (33.5 percent) considered high-risk, characterized by their young age, multiple partnerships, frequent unprotected anal intercourse, and sexual activities around MSM hotspots. In metropolitan Bangkok, HIV prevalence among MSM reportedly increased from 21 percent to 28 percent between 2000 and 2012. The Thai Working Group of Estimation and Projection (2013) projected an estimate of 39,000 new HIV infections would occur in Thailand during 2012-2016, based on the AIDS Epidemic Model (AEM). 


Keywords: HIV, transmission, heterosexual, epidemic, infections, cost-effectiveness

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Diagnostics Access Initiative to Achieve the 90-90-90 Treatment Target. UNAIDS. (2015)

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The aim of the new initiative is to leverage improved, accessible, affordable and  optimally used diagnostic technologies and strategies to ensure achievement of a bold new HIV treatment target for 2020.

 

 


Keywords: HIV, treatment cascade, testing, prevention, ART, diagnostics

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Community-based Antiretroviral Therapy Delivery. UNAIDS and Medecins sans Frontieres. (2015)

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This document presents experiences of how community-based antiretroviral therapy (ART) delivery can improve both the level of access to treatment and the quality of health outcomes for people living with HIV. These experiences illustrate that community-based ART delivery is efficient, effective and high quality.


Keywords: HIV, patient, clinical, treatment, testing, medication

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Hepatitis C Medicines Technology and Market Landscape. Isbell M, Ridzon R and Timmermans K. (2015)

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This landscape analysis surveys the current state of technologies for the treatment of hepatitis C virus (HCV), as well as market dynamics that affect the affordability and accessibility of HCV therapeutics. HCV treatment falls within the ambit of UNITAID’s mission because it is a major HIV coinfection and a leading cause of morbidity and mortality among people living with HIV. Strategic Objective 3 of the UNITAID Strategy 2013−2016 specifically refers to viral hepatitis, notably hepatitis B and C.


Keywords: HIV, HCV, medicines, infection, prevalence 

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Diagnostics Access Initiative to Achieve the 90-90-90 Treatment Target. UNAIDS. (2015)

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The aim of the new initiative is to leverage improved, accessible, affordable and  optimally used diagnostic technologies and strategies to ensure achievement of a bold new HIV treatment target for 2020.

 

 


Keywords: HIV, treatment cascade, testing, prevention, ART, diagnostics

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Implications of the START Study Data — Questions and Answers. UNAIDS. (2015)

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UNAIDS welcomes additional evidence released in May 2015 that early initiation of antiretroviral therapy has a positive effect on the health and well-being of people living with HIV. The United States National Institutes of Health-funded international randomized clinical trial START (Strategic Timing of Antiretroviral Treatment) has found compelling evidence that the benefits of starting antiretroviral therapy as soon as someone is diagnosed outweigh the risks of delaying until their CD4 count has fallen to 350 cells/mm3.

 


Keywords: HIV, AIDS, 90–90–90, treatment, human rights, testing, communities, prevention, health care, fast-track

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Fast-Tracking HIV Treatment: Parliamentary Action and Policy Options. Inter-Parliamentary Union and UNAIDS. (2015)

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HIV treatment is a cornerstone of the AIDS response, helping to prevent AIDS-related deaths and avert new infections. It also helps people living with HIV to live close-to-normal lifespans, thereby reducing HIV-related stigma. Evidence shows that HIV treatment, administered ideally as soon as possible after diagnosis, not only slows disease progression but also prevents onward HIV transmission. Moreover, the right to the highest attainable standard of health necessitates access to treatment and other medicines to ensure that people living with HIV can have long and productive lives.

 

Keywords: HIV, treatment, human rights, Fast-Track, medicines, financing

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Fast-Track Cities: Update 2015. UNAIDS. (2015)

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Launched only a year ago, Fast-Track cities has rapidly taken root and grown. This is the first annual update on progress in implementing the Fast-Track cities approach and it supports one of the seven key commitments contained in the Paris Declaration. This report reflects on the actions taken by cities and by the four core partners— the city of Paris, UNAIDS, the United Nations Human Settlements Programme (UN-Habitat) and the International Association of Providers of AIDS Care (IAPAC)—towards ending the AIDS epidemic as a public health threat by 2030. Future reports will illustrate good practices and quantifiable evidence of progress that will inspire and inform Fast-Track cities and the many stakeholders helping to confront AIDS as a health and development challenge.

 

Keywords: treatment, urban, AIDS epidemic, response, 90-90-90

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Transmitted HIV Drug Resistance Survey in Two Provinces in Papua New Guinea​​. Lavu E, Dala N, Gurung A, et al. (2015)

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Surveillance of transmitted HIV drug resistance (TDR) in individuals recently infected with HIV was performed following WHO-suggested methods. The prevalence of transmitted HIV drug resistance (TDR) in recently infected antiretroviral drug naïve individuals in PNG has not been fully characterised.


Keywords: HIV, ART, PNG, drug, Port Moresby, Mt Hagen

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