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The 2018 United Nations General Assembly High-Level Meeting (HLM) on Tuberculosis and the current revision of the Roadmap for childhood tuberculosis together present an important moment to consolidate and advance advocacy, commitment, resource mobilization and joint efforts by all stakeholders to provide health care and address the burden of TB among children.
This document compiles examples of best practices at global, regional and country levels since the launch of the first edition of the Roadmap. It describes 36 examples from 24 countries (including 10 TB, two multidrug-resistant TB (MDR-TB) and four TB/ human immunodeficiency virus (HIV) high burden countries) from all the six WHO regions, two regional initiatives and 12 global initiatives. The examples are categorized according to the ten key actions from the 2013 Roadmap.
Tuberculosis (TB) in now the leading infectious killer in the world, having surpassed HIV, and is among the top 10 causes of death worldwide. In 2016, 1.7 million people worldwide died of TB, including 400 000 TB deaths among people living with HIV. The Sustainable Development Goals call for action to end the TB epidemic as a public health threat by 2030, but the pace of progress currently is too slow to achieve this milestone.
Keywords: TB, HIV, resources, cost-effectiveness, intervention
This document contains a series of desk reviews for the eight ENGAGE-TB priority countries supported by the Global Fund (DRC, Kenya, Indonesia, Mozambique, Myanmar, Nigeria, Pakistan and Tanzania). The document provides a situation assessment and gap analysis about the state of community based TB activities in these countries. The focus on these eight countries was justified by the high prevalence of TB and the very high number of missed/unreported cases. To develop the profiles, Global Fund applications, national TB strategic plans and reports, programme review reports, relevant national guidelines and websites of the community stakeholders were examined.
TB patients and health-care providers are surrounded by information and communication technologies. They will be using these tools increasingly to obtain better care. However, in doing so they are often faced with basic questions, such as: Which application is best suited to my circumstances? What is the evidence for effectiveness? How do I implement it? Who will pay?
This handbook aims to address some of these questions. It focuses specifically on three technologies that are being widely used to help TB patients complete their treatment over the many months that their regimens last.
In this context, the purpose of the landscape analysis is ultimately to facilitate improved engagement of private providers, thereby contributing to universal access to quality and affordable TB care and the end of the TB epidemic. It focuses on the role of private for-profit providers and on specific challenges and experiences in engaging them for TB prevention and care.
This document aims to provide concrete, pragmatic guidance for how TB modelling and related technical assistance is undertaken to support country decision-making. The target audience for this document are the participants and stakeholders in country-level TB modelling efforts, including the individuals who build and apply models; policy-makers, technical experts and other members of the TB community; international funding and technical partners; and individuals and organizations engaged in supporting TB policy-making.
In 2017, 3.6 million of the estimated 10 million people with TB worldwide were “missed” by national TB programmes (NTPs). Two thirds of them are thought to access TB treatment of questionable quality from public and private providers who are not engaged by the NTP. The quality of care provided in these settings is often not known or substandard. Closing these gaps and ensuring patient-centred care imply that quality-assured and affordable TB services must be made available wherever people choose to seek care.
Keywords: TB, funding, investment, services, treatment
The report – “Antibacterial agents in clinical development – an analysis of the antibacterial clinical development pipeline, including Mycobacterium tuberculosis” – shows a serious lack of new antibiotics under development to combat the growing threat of antimicrobial resistance. Most of the drugs currently in the clinical pipeline are modifications of existing classes of antibiotics and are only short-term solutions. The report found very few potential treatment options for those antibiotic-resistant infections identified by WHO as posing the greatest threat to health, including drug-resistant tuberculosis which kills around 250 000 people each year. In addition to multidrug-resistant tuberculosis, WHO has identified 12 classes of priority pathogens – some of them causing common infections such as pneumonia or urinary tract infections – that are increasingly resistant to existing antibiotics and urgently in need of new treatments.
This is the second SEAR TB Report as we take first steps into the post 2015 era of the SDGs. In 2015, there was an estimated 4.74 million incidence of TB in the SEA Region, including HIV+TB co-infection. The total number of new cases notified to National TB programmes in the Region were around 2.65 million in appear staggering despite a reasonably good performance. Three countries that are poised well to eliminating TB by 2030 are Maldives, Bhutan and Sri Lanka. Nepal too is doing well despite the twin challenges of its mountainous terrain and coping with a major natural disaster. Timor-Leste, though small in terms of absolute TB numbers, faces a major challenge in bringing down its incidence rate.