Joint WHO/UNAIDS Annual Consultation with Pharmaceutical Companies and Stakeholders on Forecasting Global Demand of Antiretroviral Drugs for 2013-2016. WHO. (2014)

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The World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS) Secretariat jointly organized an annual two-day consultation with pharmaceutical companies and stakeholders to present them with the draft forecasts for the demand of antiretroviral (ARV) drugs in 2013–2016.

 

Keywords: Anti-Retroviral agents, supply and distribution, HIV infections, therapy, drug industry

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The Trans-Pacific Partnership Agreement: Implications for Access to Medicines and Public Health. Bhardwaj K and Oh C. (2014)

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The objective of this report is to provide an analysis of the provisions in the proposed TPPA in order to obtain a clearer understanding of their implications. It is hoped that the report will also be a useful resource for other stakeholders in the public health field.

The report analyses the key negotiating issues in the USA’s proposals (widely considered to be the basic negotiation text for the TPPA) which are likely to have an impact on access to medicines and public health.


Keywords: HIV, health, access, medicines, financing, 

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Antiretroviral Medicines in Low- and Middle-income Countries: Forecasts of Global and Regional Demand for 2013-2016. WHO. (2014)

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The global effort to scale-up HIV treatment in low- and middle-income countries continues to move closer towards achieving the goal of 15 million people receiving treatment by 2015. By the end of 2012, 9.7 million people in low- and middle-income countries were receiving antiretroviral therapy (ART), which represents an increase of 1.7 million from the previous year.

The goal of this report is to provide countries and suppliers with a sense of how the global market for antiretroviral (ARV) medicines in low- and middle-income countries is likely to evolve from 2013 to 2016. The report also aims to provide suppliers with a global forecast of the estimated demand for active pharmaceutical ingredients (APIs) so that they can manage their manufacturing capacity accordingly.


Keywords: HIV, ARV, infections, therapy, drug, adults, children

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Increasing Access to HIV Treatment in Middle-income Countries: Key Data on Prices, Regulatory Status, Tariffs and the Intellectual Property Situation. WHO. (2014)

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The paper provides information on the prices paid by 20 middle-income countries for adult and paediatric formulations of antiretroviral treatments recommended by WHO. It links this information with an analysis of the intellectual property situation of the selected medicines taking into account existing license agreements as well as compulsory licenses, and includes data and general information on a number of other determinants of prices and availability of ARVs, including tariffs, markups and taxes, as well as the regulatory status. 

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Fiji Policy on Prevention of Parent to Child Transmission (PPTCT) of HIV. Ministry Of Health- Republic of Fiji. (2014)

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Prevention of mother to child transmission of HIV has contributed to the reduction in the number of vertical transmission in Fiji. There has been an increasing focus on prevention of parent to child transmission (PPTCT) with the provision of HIV testing to pregnant women attending antenatal clinics (ANCs). Globally and nationally we have seen PPTCT services reduce HIV infections in children.

The need for Prevention of Transmission of HIV from Parents to Child is paramount for the Ministry to achieve its targets of Zero New HIV Infections which prevents transmission of HIV from Parent to Child, and secondly to reduce maternal deaths secondary to any AIDS related Illness, which contributes to Millenium Development Goal 5 and Zero AIDS related deaths Goals by UN.

PPTCT in Fiji has come a long way since the beginning more than 10 years ago. The health facility services have changed significantly. There wasn’t treatment before for mothers who were HIV positive but since the program of PPTCT came into the picture HIV positive families are able to have children who are negative for HIV. We have seen many success stories in the country.


Keywords: counselling, testing, clinic, treatment, prevention, women

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Antimicrobial Resistance: Global Report on Surveillance. WHO. (2014)

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The report is intended to provide information primarily for public health policy-makers and managers, and for the wider medical and public health community (including pharmaceutical companies), as a support for informing strategic actions and programme planning. It will also be of interest to the other sectors that are directly involved, including veterinary drug and animal husbandry, agriculture and aquaculture.


Keywords: HIV, drug resistance, tuberculosis (TB), medicines

 


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UNITAID’s Key Performance Indicators 2013 - Transforming Markets Adding Value. UNITAID. (2014)

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UNITAID was launched in 2006 at the United Nations General Assembly by the governments of Brazil, Chile, France, Norway and the United Kingdom to improve access to vital medicines, tests and prevention products for people living with HIV/AIDS, TB and malaria in low income countries. Its pioneering investments, financed significantly by an air ticket levy, have shaped the markets for paediatric and second line medicines for HIV/AIDS, new diagnostic tools to detect TB and the provision of ACTs to private sector outlets where up to 60% of people seek treatment for malaria in high burden countries. Reflecting on these accomplishments and looking to address gaps in the availability and affordability of life-saving products for the three diseases, UNITAID produced a new strategy for 2013-2016.

 

Keywords: HIV/AIDS, TB, malaria, medicines, diagnostics, paediatric, treatment

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HIV Medicines Technology and Market Landscape - 1st Edition. UNITAID. (2014)

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Access to appropriate antiretroviral therapy (ART) is vital to prevent HIV morbidity and mortality, and high ART coverage also promotes HIV prevention by lowering the amount of virus circulating in people within a particular setting or population. The World Health Organization (WHO) released new treatment recommendations in June 2013 that raise the CD4 cell count threshold for ART initiation for most people (from 350 to 500 cells/mL) and expand the number of populations that should receive treatment irrespective of their immune status. These changes have substantially increased the number of people eligible for ART. At the end of 2012, almost 10 million people were receiving ART in low- and middle-income countries, or about 34% of the total eligible population under the 2013 WHO treatment guidelines (28.6 million). The access level in children was falling behind at an estimated 20% of the total paediatric population in need of ART; while 647 000 children were receiving ART as of December 2012, an additional 2.6 million children were eligible for ART under current WHO treatment guidelines, but not receiving it.


Keywords: HIV, ARV, treatment, infant, children, medicines

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Assessing the Impact of Alternative Patent Systems on the Cost of Health Care: The TPPA and HIV Treatment in Vietnam. Moir H V J, Tenni B, Gleeson D and Lopert R. (2014)

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In the Trans Pacific partnership Agreement (TPPA) negotiations, the United States has proposed expanded patent protections that will likely impact the affordability of medicines in TPPA partners. This includes antiretroviral (ARV) medicines used in the treatment of HIV/AIDS. Vietnam has the lowest GDP per capita of the 12 countries participating in the TPPA negotiations. Using the current Vietnamese patent regime as our base case, we analyse the potential impact of alternative patent regimes on access to ARVs in Vietnam. The two other scenarios investigated are a patent regime making full use of TRIPS flexibilities, and a regime based on the US proposals in the 2014 leaked draft of the TPPA intellectual property chapter. Using World Health Organization (WHO) treatment guidelines, we identified the most commonly used chemical entities and combinations used in the treatment of HIV. We examined patent data sets to discover patents that had been registered for these medicines and used information from examination of these patents to identify which might be granted under alternative patent regimes. We then drew on the empirical literature to estimate prices under the three patent scenarios. The current ARV budget was used as a constraint, with the consequence that the results focus on the impact of alternative patent regimes on access to treatment. Our results indicate 82% of the HIV population eligible for treatment would receive ARVs under a full TRIPS flexibility scenario, while only 30% of Vietnam's eligible HIV patients would have access to ARVs under the US 2014 TPPA proposals – more than halving the proportion treated compared to the current 68% receiving treatment. Similar price impacts can be expected for other countries participating in the TPPA, though these are less economically vulnerable than Vietnam.

 


Keywords: TPPA, patent policy, trade policy, access to medicines, Vietnam

 

 

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An Ambitious Treatment Target to Help End the AIDS Epidemic. UNAIDS. (2014)

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HIV treatment is a unique tool in the AIDS response, preventing illness and death, averting new infections and saving money. As hopes for ending the AIDS epidemic depend  in large measure on the world’s ability to provide HIV treatment to all who need it, in a rights-based approach, final targets for universal treatment access are critical.

 

Keywords: HIV, coverage, testing, antiretroviral therapy (ART), antiretroviral drugs (ARV), key populations, 90-90-90

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Highlighted publications
http://aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_Global_AIDS_Update_2017.pdf
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http://aidsdatahub.org/sites/default/files/highlight-reference/document/India_IBBS_report_2014-15.pdf
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http://aidsdatahub.org/sites/default/files/highlight-reference/document/Death_Penalty_for_Drug_Offences_Global_Overview_2015.pdf
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http://aidsdatahub.org/sites/default/files/highlight-reference/document/WHO_Consolidated_on_the_use_of_antiretroviral_drugs_for_treating_and_preventing_HIV_infection_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/Consolidated_Strategic_Information_Guidelines_for_HIV_in_Health_Sector_2015.pdf
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