Issue Brief: Hepatitis C and Drug Pricing: The Need for a Better Balance. amfAR. (2015)

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In this brief, we review drug pricing for new hepatitis C medications and pose basic questions of fairness and medical ethics. Although we focus on Gilead and its hepatitis C drug sofosbuvir, the issues we highlight are broadly applicable to other manufacturers of hepatitis C medications.


Keywords: HIV, HCV, prevalence, treatment, cost

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Transmitted HIV Drug Resistance Survey in Two Provinces in Papua New Guinea​​. Lavu E, Dala N, Gurung A, et al. (2015)

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Surveillance of transmitted HIV drug resistance (TDR) in individuals recently infected with HIV was performed following WHO-suggested methods. The prevalence of transmitted HIV drug resistance (TDR) in recently infected antiretroviral drug naïve individuals in PNG has not been fully characterised.


Keywords: HIV, ART, PNG, drug, Port Moresby, Mt Hagen

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Overview of regional implementation of the Political Declaration on HIV/AIDS and the Millennium Development Goals and Efforts to Ensure Universal Access in Asia and the Pacific. ESCAP. (2015)

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The present document aims to review the progress of the HIV response in the Asia-Pacific region, with a view to identifying the opportunities for further action afforded by the 2011 Political Declaration. In doing so, it also draws on the expressed commitments undertaken by ESCAP member States to address the HIV epidemic, including those reflected in resolutions 66/10, Regional call for action to achieve universal access to HIV prevention, treatment, care and support in Asia and the Pacific (19 May 2010) and 67/9, Asia-Pacific regional review of the progress achieved in realizing the Declaration of Commitment on HIV/AIDS and the Political Declaration on HIV/AIDS (25 May 2011).

 

Keywords: IGM, 2015, HIV, prevalence, treatment, care, prevention, gender, violence, ART, children, women

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Hepatitis C Medicines Technology and Market Landscape. Isbell M, Ridzon R and Timmermans K. (2015)

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This landscape analysis surveys the current state of technologies for the treatment of hepatitis C virus (HCV), as well as market dynamics that affect the affordability and accessibility of HCV therapeutics. HCV treatment falls within the ambit of UNITAID’s mission because it is a major HIV coinfection and a leading cause of morbidity and mortality among people living with HIV. Strategic Objective 3 of the UNITAID Strategy 2013−2016 specifically refers to viral hepatitis, notably hepatitis B and C.


Keywords: HIV, HCV, medicines, infection, prevalence 

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Transmitted HIV Drug Resistance Survey in Two Provinces in Papua New Guinea. Lavu E, Dala N, Gurung A, et al. (2015)

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Surveillance of transmitted HIV drug resistance (TDR) in individuals recently infected with HIV was performed following WHO-suggested methods. The prevalence of transmitted HIV drug resistance (TDR) in recently infected antiretroviral drug naïve individuals in PNG has not been fully characterised.


Keywords: HIV, ART, PNG, prevalence, drug resistance

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ART Cohort Analysis Report-Sri Lanka, 2015. National STD/AIDS Control Programme, Sri Lanka. (2015)

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This document provides Cohort analysis for patients who started ART in 2013 (12 months), Cohort analysis for patients who started ART in 2012 (24 months) and Cohort analysis for patients who started ART in 2009 (60 months).

 

Keywords: ART, treatment, clinic, deaths

 

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Towards HIV Treatment on Demand for All. Health GAP and Partners. (2015)

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The world faces an important window of opportunity in the trajectory of the global AIDS response. New scientific evidence shows that starting HIV treatment immediately upon diagnosis enables people to live longer, healthier lives and is among the most effective ways to prevent HIV transmission. Several years ago, in response to this evidence, some countries began providing all people living with HIV access to immediate treatment.


Keywords: HIV, CD4, treatment, diagnosis, policy, human rights

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Programmatic Update on Antiretrovirals: Maximizing the Treatment and Prevention Potential of Antiretroviral Drugs: Early Country Experiences towards Implementing a Treat-all Policy. WHO. (2015)

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WHO guidelines on antiretroviral therapy (ART) have evolved during the past decade towards recommending earlier treatment, as evidence has shown clinical and public health benefit, treatment has become simpler, more tolerable and more affordable, and systems for ARV delivery have been streamlined for scale.

This update summarizes experiences of countries that have already begun to implement earlier treatment approaches as part of a national policy or pilot programmes. Overall, these five country examples demonstrate that scaling up a treat-all policy, across diverse populations (adults, key populations and children) is acceptable and feasible, with early benefits and no immediate evidence of harmful effects.


Keywords: HIV, ART, treatment, prevention, key populations 

 

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Preventing HIV Transmission in Intimate Partner Relationships: Evidence, Strategies and Approaches for Addressing Concentrated HIV Epidemics in Asia. UNDP. (2015)

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Preventing HIV Transmission in Intimate Partner Relationships: Evidence, strategies and approaches for addressing concentrated HIV epidemics in Asia provides evidence-based guidance to policymakers in Asia so that national HIV responses give appropriate priority to prevention efforts among key populations and their intimate partners, as well as those in serodiscordant relationships. Scaling up efforts to prevent intimate partner transmission of HIV will help countries to meet targets to halve sexual transmission of HIV, eliminate mother-to-child transmission, reduce AIDS-related maternal deaths, and address gender inequalities. 


This report by UNDP, UNICEF and UNAIDS responds to data which shows that new infections in the long-running HIV epidemics in Asia, such as in Cambodia, China, India, Indonesia, Myanmar and Thailand, are on the increase among intimate partners of high risk populations.  Reviewing the interplay of factors that affect sexual behaviours and decision making among key populations and people living with HIV, the report recommends strategies that need to be adopted by countries for a more comprehensive response to intimate partner transmission.


The report argues that efforts to address intimate partner transmission of HIV should concentrate on the interplay of factors that affect sexual behaviour and decision-making among key populations and people living with HIV who know their status, including how they negotiate safer sex and make contraceptive choices with their intimate partners.


Keywords: HIV, prevention, human rights, PMTCT, PLHIV, gender equality, violence


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Download summary report click here

 

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- Evidence on high intimate partner transmission

 

- Common determinants of risk and vulnerability (i) men from key populations; (ii) women from key populations; and (iii) in serodiscordant couple relationships

 

- Five high impact strategies for preventing HIV in intimate partner relationships

 

- Components of a combination prevention approach for preventing HIV in intimate partner relationships

 

- Recommendations

 

Global Action Plan on Antimicrobial Resistance. WHO. (2015)

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Antimicrobial resistance threatens the very core of modern medicine and the sustainability of an effective, global public health response to the enduring threat from infectious diseases. Systematic misuse and overuse of these drugs in human medicine and food production have put every nation at risk. Few replacement products are in the pipeline. Without harmonized and immediate action on a global scale, the world is heading towards a post-antibiotic era in which common infections could once again kill.


Keywords: awareness, prevention, medicines, diagnostic, vaccines

 

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