Fast-Tracking Combination Prevention. UNAIDS. (2015)

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To reduce new HIV infections globally to fewer than 500 000 by 2020, a step towards ending the HIV epidemic as a public health threat by 2030, we need to Fast-Track the response, including renewed commitment to, sustained funding for and scaled-up implementation of HIV prevention programmes.

 

Keywords: HIV prevention, young women, partners, PrEP, male circumcision

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Every Newborn: An Action Plan to End Preventable Deaths. WHO and UNICEF. (2014)

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The action plan sets out a vision of a world in which there are no preventable deaths of newborns or stillbirths, where every pregnancy is wanted, every birth celebrated and women, babies and children survive, thrive and reach their full potential. Nearly 3 million lives could be saved each year if the actions in the plan are implemented and its goals and targets achieved. Based on evidence of what works, and developed within the framework for Every Woman Every Child, the plan enhances and supports coordinated, comprehensive planning and implementation of newborn specific actions within the context of national reproductive, maternal, newborn, child and adolescent health (RMNCAH) strategies and action plans, and in collaboration with stakeholders from the private sector, civil society, professional associations and others. The goal is to achieve equitable and high quality coverage of care for all women and newborns through links with other global and national plans, measurement and accountability.


Keywords: infant mortality, prevention and control, newborn, stillbirth, perinatal care, pregnancy outcome

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Hepatitis C Silent Killer Behind HIV. Department of Health, Hong Kong. (2014)

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In Hong Kong, the estimated HCV prevalence in general population is around 0.3%.

 

In the last decade, there have been increasing overseas reports of acute HCV infections via sexual transmission in men who have sex with men (MSM), especially those who were HIV positive. Locally, the prevalence of HCV in the HIV infected MSM seen at the Department of Health (DH) was found to be 1.3% for the years 2000-2012, which is 4 times that of the general population. In addition, rising trend of the infection among local HIV infected MSM has been observed in recent years. In 2013, a case series of sexually transmitted HCV infections among HIV infected MSM was found by DH.


Keywords: HIV, HCV, sexual transmission, diagnosis

 

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Surveillance of HIV Drug Resistance in Populations Initiating Antiretroviral Therapy (Pre-treatment HIV Drug Resistance). WHO. (2014)

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Nationally representative surveillance of HIVDR in populations initiating a standard triple-drug ART combination is critical to inform the selection of effective first-line ART combinations, as well as adequate pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) regimens. Detected HIVDR in populations initiating triple-drug ART regimens may have been transmitted at the time of initial infection or acquired due to previous exposure to antiretroviral (ARV) drugs (in the context of prevention of mother-to-child transmission (PMTCT) programmes, PrEP, PEP or previous disclosed or undisclosed ART).

 

Keywords: HIV, drug resistance, infections, epidemiology, therapy, surveillance

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UNITAID’s Key Performance Indicators 2013 - Transforming Markets Adding Value. UNITAID. (2014)

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UNITAID was launched in 2006 at the United Nations General Assembly by the governments of Brazil, Chile, France, Norway and the United Kingdom to improve access to vital medicines, tests and prevention products for people living with HIV/AIDS, TB and malaria in low income countries. Its pioneering investments, financed significantly by an air ticket levy, have shaped the markets for paediatric and second line medicines for HIV/AIDS, new diagnostic tools to detect TB and the provision of ACTs to private sector outlets where up to 60% of people seek treatment for malaria in high burden countries. Reflecting on these accomplishments and looking to address gaps in the availability and affordability of life-saving products for the three diseases, UNITAID produced a new strategy for 2013-2016.

 

Keywords: HIV/AIDS, TB, malaria, medicines, diagnostics, paediatric, treatment

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Assessing the Impact of Alternative Patent Systems on the Cost of Health Care: The TPPA and HIV Treatment in Vietnam. Moir H V J, Tenni B, Gleeson D and Lopert R. (2014)

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In the Trans Pacific partnership Agreement (TPPA) negotiations, the United States has proposed expanded patent protections that will likely impact the affordability of medicines in TPPA partners. This includes antiretroviral (ARV) medicines used in the treatment of HIV/AIDS. Vietnam has the lowest GDP per capita of the 12 countries participating in the TPPA negotiations. Using the current Vietnamese patent regime as our base case, we analyse the potential impact of alternative patent regimes on access to ARVs in Vietnam. The two other scenarios investigated are a patent regime making full use of TRIPS flexibilities, and a regime based on the US proposals in the 2014 leaked draft of the TPPA intellectual property chapter. Using World Health Organization (WHO) treatment guidelines, we identified the most commonly used chemical entities and combinations used in the treatment of HIV. We examined patent data sets to discover patents that had been registered for these medicines and used information from examination of these patents to identify which might be granted under alternative patent regimes. We then drew on the empirical literature to estimate prices under the three patent scenarios. The current ARV budget was used as a constraint, with the consequence that the results focus on the impact of alternative patent regimes on access to treatment. Our results indicate 82% of the HIV population eligible for treatment would receive ARVs under a full TRIPS flexibility scenario, while only 30% of Vietnam's eligible HIV patients would have access to ARVs under the US 2014 TPPA proposals – more than halving the proportion treated compared to the current 68% receiving treatment. Similar price impacts can be expected for other countries participating in the TPPA, though these are less economically vulnerable than Vietnam.

 


Keywords: TPPA, patent policy, trade policy, access to medicines, Vietnam

 

 

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Dual Elimination of Mother-to-child Transmission of HIV and Congenital Syphilis. UNITAID. (2014)

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There are more than one hundred HIV rapid tests commercially available today, all of which can be used for screening pregnant women for the virus. These tests, which are generally antibody tests, have been widely adopted, especially in resource-limited settings, where they can be used in decentralized facilities, including prevention of mother-to-child transmission (PMTCT) and voluntary counselling and testing (VCT) centres, to provide same-day results to patients. In general, the technical performance of these HIV rapid tests, as reported by manufacturers, is strong. Sensitivities usually range from 99.3% to 100% and specificities range from 99.7% to 99.9%.


Keywords: HIV, syphilis, PMTCT, children, pregnant women, prevention

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Annual Report 2013. UNITAID. (2014)

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UNITAID’s Strategy 2013-2016 guides the organization’s response to HIV/AIDS, malaria and TB. In total, these global epidemics kill almost 4 million people every year. Forward looking and flexible, UNITAID collects intelligence on product markets for these diseases in order to inform its investments, which are implemented by the world’s top development organizations.

 

Keywords: HIV/AIDS, TB, malaria, medicines, diagnostics, prevention

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March 2014 Supplement to the 2013 Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection. WHO. (2014)

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WHO guidelines on the use of antiretroviral (ARV) drugs for treating and preventing HIV infection provide a public health approach for scaling up HIV care and treatment programmes and focus on simplified, harmonized and effective antiretroviral therapy (ART) regimens for use in resource-limited settings. In 2013, for the first time, WHO revised and combined guidelines for adults and adolescents, infants and children and pregnant women as well as other ARV-related guidance documents into one set of consolidated guidelines that addressed the use of ARV drugs for HIV treatment and prevention across all age groups and populations, based on the broad continuum of HIV care.

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UNITAID Strategy 2013-2016. UNITAID. (2013)

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The purpose of UNITAID is to contribute to the achievement of global long-term goals for HIV, tuberculosis and malaria through its interventions in product markets. These goals have determined the Strategic Objectives described in this Strategy for the coming four years and are shared by the international community at large.

 

Keywords: HIV/AIDS, TB, malaria, medicines, funding, diagnostics, prevention

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Highlighted publications
http://aidsdatahub.org/sites/default/files/highlight-reference/document/Nepal-IBBS-FIDU-Kathmandu-valley-RI-2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_Get_on_the_Fast-Track_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/NEC_HIV_July-Oct-AIDSreg2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_methods_for_deriving_estimates_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_Global_AIDS_Response_Progress_Reporting_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/2015_Size_Estimation_of_Key_Affected_Populations_in_Philippines.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/Assessment_of_Decentralization_of_ART_in_MMR_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS-2016-prevention-gap-report_en.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_AIDS_by_the_numbers_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_Biomedical_AIDS_research_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/Implementing_comprehensive_HIV_and_STI_programmes_with_transgender_people_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_cities_ending_the_aids_epidemic_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/Philippines_2015_IHBSS_Factsheets.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/Pakistan_IBBS_Report_Punjab_2014_0.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/WHO_Integrating_collaborative_TB_and_HIV_services_within_a_comprehensive_package_of_care_for_PWID_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/India_IBBS_report_2014-15.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/India_HSS_report_2014-15.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/The_negative_impact_of_drug_control_on_public_health_2015.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/2015_young_people_drugs_en.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/Death_Penalty_for_Drug_Offences_Global_Overview_2015.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/Transforming_our_world_2015_UN.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/WHO_Consolidated_on_the_use_of_antiretroviral_drugs_for_treating_and_preventing_HIV_infection_2016.pdf
http://aidsdatahub.org/sites/default/files/highlight-reference/document/Consolidated_Strategic_Information_Guidelines_for_HIV_in_Health_Sector_2015.pdf
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