Worldwide Country Situation Analysis: Response to Antimicrobial Resistance. WHO. (2015)


A survey was conducted in countries in all six WHO regions and focused on the building blocks that are considered prerequisites to combat antimicrobial resistance: a comprehensive national plan, laboratory capacity to undertake surveillance for resistant microorganisms, access to safe, effective antimicrobial medicines, control of the misuse of these medicines, awareness and understanding among the general public and effective infection prevention and control programmes. 

Keywords: drug resistance, microbial, infection control, surveillance


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Community-based Antiretroviral Therapy Delivery. UNAIDS and Medecins sans Frontieres. (2015)


This document presents experiences of how community-based antiretroviral therapy (ART) delivery can improve both the level of access to treatment and the quality of health outcomes for people living with HIV. These experiences illustrate that community-based ART delivery is efficient, effective and high quality.

Keywords: HIV, patient, clinical, treatment, testing, medication

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Hepatitis C Diagnostics Technology Landscape - 1st Edition. Murtagh MM. (2015)


This report describes the current continuum of testing for HCV, which is complex and expensive, which means that it is very challenging to implement in resource-limited settings. It examines the platforms/tests that are currently available across the range of required HCV testing from screening to confirmation and genotyping, fibrosis staging and treatment monitoring. The report also considers how the testing cascade for HCV may be simplified with the availability of DAAs, which would help make HCV testing attainable in resource-limited settings. Finally, it looks at the pipeline of tests/platforms for HCV that could be delivered at or near the point of patient care.


Keywords: HIV, HCV, treatment, testing, monitoring

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Implications of the START Study Data — Questions and Answers. UNAIDS. (2015)


UNAIDS welcomes additional evidence released in May 2015 that early initiation of antiretroviral therapy has a positive effect on the health and well-being of people living with HIV. The United States National Institutes of Health-funded international randomized clinical trial START (Strategic Timing of Antiretroviral Treatment) has found compelling evidence that the benefits of starting antiretroviral therapy as soon as someone is diagnosed outweigh the risks of delaying until their CD4 count has fallen to 350 cells/mm3.


Keywords: HIV, AIDS, 90–90–90, treatment, human rights, testing, communities, prevention, health care, fast-track

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Overview of regional implementation of the Political Declaration on HIV/AIDS and the Millennium Development Goals and Efforts to Ensure Universal Access in Asia and the Pacific. ESCAP. (2015)


The present document aims to review the progress of the HIV response in the Asia-Pacific region, with a view to identifying the opportunities for further action afforded by the 2011 Political Declaration. In doing so, it also draws on the expressed commitments undertaken by ESCAP member States to address the HIV epidemic, including those reflected in resolutions 66/10, Regional call for action to achieve universal access to HIV prevention, treatment, care and support in Asia and the Pacific (19 May 2010) and 67/9, Asia-Pacific regional review of the progress achieved in realizing the Declaration of Commitment on HIV/AIDS and the Political Declaration on HIV/AIDS (25 May 2011).


Keywords: IGM, 2015, HIV, prevalence, treatment, care, prevention, gender, violence, ART, children, women

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Hepatitis C Medicines Technology and Market Landscape. Isbell M, Ridzon R and Timmermans K. (2015)


This landscape analysis surveys the current state of technologies for the treatment of hepatitis C virus (HCV), as well as market dynamics that affect the affordability and accessibility of HCV therapeutics. HCV treatment falls within the ambit of UNITAID’s mission because it is a major HIV coinfection and a leading cause of morbidity and mortality among people living with HIV. Strategic Objective 3 of the UNITAID Strategy 2013−2016 specifically refers to viral hepatitis, notably hepatitis B and C.

Keywords: HIV, HCV, medicines, infection, prevalence 

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Issue Brief - Decisions Around HIV Treatment in 2015: Seven Ways to Fail, Derail or Prevail. Médecins Sans Frontières. (2015)


In this issue brief we first review trends in generic competition and intellectual property (IP) licensing for key antiretroviral drugs. We then outline seven momentous decisions to be made in 2015 that will largely determine whether ART will be affordable, available and robust for the next 15 years of treatment scale-up to all people living with HIV. This includes opportunities for greatly improved treatment regimens based on WHO guidelines on when to start treatment, and what first- and second line regimens should include.


Keywords: HIV/AIDS, Global Fund, medicines, treatment, ART

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Preventing HIV Transmission in Intimate Partner Relationships: Evidence, Strategies and Approaches for Addressing Concentrated HIV Epidemics in Asia. UNDP. (2015)


Preventing HIV Transmission in Intimate Partner Relationships: Evidence, strategies and approaches for addressing concentrated HIV epidemics in Asia provides evidence-based guidance to policymakers in Asia so that national HIV responses give appropriate priority to prevention efforts among key populations and their intimate partners, as well as those in serodiscordant relationships. Scaling up efforts to prevent intimate partner transmission of HIV will help countries to meet targets to halve sexual transmission of HIV, eliminate mother-to-child transmission, reduce AIDS-related maternal deaths, and address gender inequalities. 

This report by UNDP, UNICEF and UNAIDS responds to data which shows that new infections in the long-running HIV epidemics in Asia, such as in Cambodia, China, India, Indonesia, Myanmar and Thailand, are on the increase among intimate partners of high risk populations.  Reviewing the interplay of factors that affect sexual behaviours and decision making among key populations and people living with HIV, the report recommends strategies that need to be adopted by countries for a more comprehensive response to intimate partner transmission.

The report argues that efforts to address intimate partner transmission of HIV should concentrate on the interplay of factors that affect sexual behaviour and decision-making among key populations and people living with HIV who know their status, including how they negotiate safer sex and make contraceptive choices with their intimate partners.

Keywords: HIV, prevention, human rights, PMTCT, PLHIV, gender equality, violence

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- Evidence on high intimate partner transmission


- Common determinants of risk and vulnerability (i) men from key populations; (ii) women from key populations; and (iii) in serodiscordant couple relationships


- Five high impact strategies for preventing HIV in intimate partner relationships


- Components of a combination prevention approach for preventing HIV in intimate partner relationships


- Recommendations


Scaling up HIV Treatment for MSM in Bangkok: What Does It Take? — A Modelling and Costing Study. Zhang L, Phanuphak N, Henderson K, et al. (2015)


The HIV epidemic amongst men who have sex with men (MSM) in Bangkok is substantial. The population size of MSM in Bangkok is 120,000-250,000, with approximately one-third (33.5 percent) considered high-risk, characterized by their young age, multiple partnerships, frequent unprotected anal intercourse, and sexual activities around MSM hotspots. In metropolitan Bangkok, HIV prevalence among MSM reportedly increased from 21 percent to 28 percent between 2000 and 2012. The Thai Working Group of Estimation and Projection (2013) projected an estimate of 39,000 new HIV infections would occur in Thailand during 2012-2016, based on the AIDS Epidemic Model (AEM). 

Keywords: HIV, transmission, heterosexual, epidemic, infections, cost-effectiveness

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Diagnostics Access Initiative to Achieve the 90-90-90 Treatment Target. UNAIDS. (2015)


The aim of the new initiative is to leverage improved, accessible, affordable and  optimally used diagnostic technologies and strategies to ensure achievement of a bold new HIV treatment target for 2020.



Keywords: HIV, treatment cascade, testing, prevention, ART, diagnostics

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